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(-)-Corey lactone diol

COREY LACTONE DIOL

CAS: 32233-40-2

Molecular Formula: C8H12O4

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(-)-Corey lactone diol - Names and Identifiers

Name COREY LACTONE DIOL
Synonyms Lactone diol
(-)-Coreydiol
COREY LACTONE DIOL
(-) COREY LACTONE DIOL
(-)-Corey Lactone Diol
(+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
(1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
(3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,
(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
(1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone
(3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-,(3aR,4S,5R,6aS)-
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, (3aR,4S,5R,6aS)-
(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
CAS 32233-40-2
EINECS 608-721-8
InChI InChI=1/C8H12O4/c9-3-5-4-1-8(11)12-7(4)2-6(5)10/h4-7,9-10H,1-3H2/t4-,5-,6-,7+/m1/s1
InChIKey VYTZWRCSPHQSFX-GBNDHIKLSA-N

(-)-Corey lactone diol - Physico-chemical Properties

Molecular FormulaC8H12O4
Molar Mass172.18
Density1.2104 (rough estimate)
Melting Point117-119°C(lit.)
Boling Point262.49°C (rough estimate)
Flash Point172.9°C
Solubility DMSO (Slightly), Methanol (Slightly)
Vapor Presure2.63E-08mmHg at 25°C
AppearanceCrystalline Powder or Crystals
ColorWhite to beige-brown
pKa14.36±0.40(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.4455 (estimate)
Physical and Chemical PropertiesMelting Point: 116 - 118

(-)-Corey lactone diol - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
WGK Germany3
HS Code29322090

(-)-Corey lactone diol - Reference Information

Application Collinalidiol is an intermediate of iloprost (I267300) and has inhibitory activity on endamidase. Iloprost (I267300) is a synthetic prostacyclin (PGI2) analog used to treat pulmonary hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
use colinoid diol is used as prostaglandin bulk drug, pharmaceutical synthesis intermediate, etc.
biological activity (-)-Corey lactone diol is a reduced form of corey aldehyde. Blocks in chemical synthesis.
Last Update：2024-04-09 15:16:49
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View History
(-)-Corey lactone diol
rans-1-Benzoyl-4-phenyl-L-proline
Diethyl phosphorochlorodithionate
1-propan-2-ylpyrazolo[3,4-d]pyrimidine-6-carboxylic acid
terbium(+3) cation
(R)-2-METHYLSUCCINIC ACID
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